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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DAPK3
All Species:
17.88
Human Site:
S345
Identified Species:
35.76
UniProt:
O43293
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43293
NP_001339.1
454
52536
S345
G
L
R
E
L
Q
R
S
R
R
L
C
H
E
D
Chimpanzee
Pan troglodytes
XP_001140200
1430
160025
S519
E
T
P
L
L
T
A
S
A
R
G
Y
H
D
I
Rhesus Macaque
Macaca mulatta
XP_001101129
454
52535
S345
G
L
R
E
L
E
R
S
R
R
L
C
H
E
D
Dog
Lupus familis
XP_533950
454
52750
S345
G
L
R
G
L
E
H
S
R
R
L
F
H
E
D
Cat
Felis silvestris
Mouse
Mus musculus
O54784
448
51403
G340
G
L
R
E
L
Q
R
G
R
R
Q
C
R
E
R
Rat
Rattus norvegicus
O88764
448
51431
G340
G
L
R
E
L
Q
R
G
R
R
Q
C
R
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517613
524
60252
S415
G
L
R
E
L
E
H
S
K
K
L
F
R
E
D
Chicken
Gallus gallus
NP_001026784
974
109076
S519
E
T
P
L
L
T
A
S
A
R
G
Y
H
D
I
Frog
Xenopus laevis
NP_001089464
452
52318
S345
A
L
R
E
L
Q
K
S
Q
A
T
S
R
E
D
Zebra Danio
Brachydanio rerio
XP_690685
453
52525
N345
G
L
R
E
L
E
K
N
Q
R
S
C
G
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q0KHT7
784
85666
R433
Q
I
V
T
P
T
R
R
A
S
D
S
D
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWL2
534
60474
G418
R
N
G
L
H
R
L
G
S
K
L
T
E
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.9
98.9
95.3
N.A.
83.9
83.6
N.A.
76.1
34
78.1
80.4
N.A.
22.5
N.A.
N.A.
N.A.
Protein Similarity:
100
29.2
99.7
97.8
N.A.
90.9
90.7
N.A.
81.6
40.9
89.2
90.9
N.A.
35.4
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
93.3
73.3
N.A.
73.3
73.3
N.A.
60
26.6
53.3
60
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
80
N.A.
73.3
73.3
N.A.
80
33.3
66.6
86.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
17
0
25
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
0
9
17
50
% D
% Glu:
17
0
0
59
0
34
0
0
0
0
0
0
9
67
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% F
% Gly:
59
0
9
9
0
0
0
25
0
0
17
0
9
0
0
% G
% His:
0
0
0
0
9
0
17
0
0
0
0
0
42
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
17
% I
% Lys:
0
0
0
0
0
0
17
0
9
17
0
0
0
9
0
% K
% Leu:
0
67
0
25
84
0
9
0
0
0
42
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
17
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
34
0
0
17
0
17
0
0
0
0
% Q
% Arg:
9
0
67
0
0
9
42
9
42
67
0
0
34
0
17
% R
% Ser:
0
0
0
0
0
0
0
59
9
9
9
17
0
9
0
% S
% Thr:
0
17
0
9
0
25
0
0
0
0
9
9
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _